Assoc. Prof. Dr. Siti Nurbaya Oslan
Academic qualifications
Ph.D., Universiti Putra Malaysia, Malaysia
Research interest:
My research focuses on the development of a yeast expression system using Meyerozyma guilliermondii for recombinant protein expression. The metabolic pathway analysis, genome editing, and proteomic analysis are implemented to improve protein expression. The structures of the virulence factors and proteases are predicted to understand the yeast behaviors. A web-based prediction system coupled with a curated database is developed to facilitate the recombinant lipase expression in Komagataella phaffii. The new lipases and antifreeze peptide from yeast are also isolated and designed to be used in cheese making industries and others.
Selected publications:
1. Salleh, A. B., Baharuddin, S. M., Rahman, N. Z. R. A., Leow, T. C., Basri, M., Oslan, S. N. (2020). A host-vector system for the expression of a thermostable bacterial lipase in a locally isolated Meyerozyma guilliermondii SMB. Microorganisms, 8, 1738. doi.org/10.3390/microorganisms8111738
2. Lim, S. J., Noor, N. D.M., Salleh, A. B., Oslan, SN. N. (2020). Structure prediction of a thermostable SR74 α-amylase from Geobacillus stearothermophilus expressed in CTG-clade yeast Meyerozyma guilliermondii strain SO. Catalysts, 10(9), 1059. doi.org/10.3390/catal10091059
3. Abu, M. L., Mohammad, R., Oslan, S.N., Salleh, A. B. (2020). The use of response surface methodology for enhanced production of a thermostable bacterial lipase in a novel yeast system. Preparative Biochemistry & Biotechnology, 1818256. doi.org/10.1080/10826068.2020.1818256
4. Nasir, N. S. M., Leow, T. C., Oslan, S. N. H., Salleh, A. B., Oslan, S. N. (2020). Molecular expression of a recombinant thermostable bacterial amylase from Geobacillus stearothermophilus SR74 using methanol-free Meyerozyma guilliermondii strain SO yeast system. BioResources, 15(2), 3161-3172.
5. Eskandari, A., Leow, T. C., Rahman, M. B. A., Oslan, S. N. (2020). Antifreeze proteins and their practical utilization in industry, medicine, and agriculture. Biomolecules, 10, 1649. 10.3390/biom10121649
ORCID ID
https://orcid.org/0000-0003-0143-425X
Google Scholar
https://scholar.google.com/citations?user=MxmhjjkAAAAJ&hl=en
E-mail: snurbayaoslan@upm.edu.my