WATER SECURITY RESEARCH GROUP

HUMAN HEALTH RISK

Literatures on pharmaceuticals in drinking water were very limited in Malaysia. This limited information has led to unclear human health impacts from this in drinking water of Malaysia. Thus, this study is intended to determine top ten active pharmaceuticals ingredient concentrations (Glibenclamide, Atenolol, Metformin, Metoprolol, Nifedipine, Simvastatin, Amlodipine, Salbutamol, Chlorpheniramine and Gliclazide) in drinking water in Malaysia using in vitro digestion model.


This study is also will use the bioavailable form of pharmaceuticals to evaluate health risks from pharmaceuticals exposure via drinking water using Health Risk Assessment. The Predicted No Effects Concentrations values for all the investigated active pharmaceutical ingredients in drinking water will determine the health impacts due these pharmaceutical exposures in drinking water.


This study is expected to provide evidence that incorporation of pharmaceutical investigation in in drinking water along with health risk assessment can give clear picture and fulfil the knowledge gaps on exposure of pharmaceutical residues through drinking water.


This study also potential to be used to look into cost-effective methods to prioritize pharmaceuticals within the context of an overall human and environmental risk assessments.


CURRENT SUMMARY OF FINDINGS

1. ELISA kits have been purchased and analysis are going on

2. Pharmaceuticals determination is going on using surface water

3. Pharmaceuticals were detected in surface water